Tès san jeneral ak byochimik nan chen: dechifre endikatè yo
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Tès san jeneral ak byochimik nan chen: dechifre endikatè yo

Tès san jeneral ak byochimik nan chen: dechifre endikatè yo

Types of blood tests in dogs

There are many types of tests and blood counts in dogs, we will discuss the most important of them: the general clinical analysis (CCA) and the biochemical blood test (BC). An experienced clinician, by comparing the history and test results, can determine which direction to choose in the diagnosis and how to help the patient.

Tès san jeneral ak byochimik nan chen: dechifre endikatè yo

Analiz jeneral

A complete blood count in dogs will show signs of infection, the intensity of the inflammatory process, anemic conditions and other abnormalities.

Faktè prensipal:

  • Hematocrit (Ht) – the percentage of red blood cells in relation to the volume of blood. The more red blood cells in the blood, the higher this indicator will be. This is the main marker of anemia. An increase in hematocrit usually does not carry much clinical significance, while its decrease is a bad sign.

  • Hemoglobin (Hb) – a protein complex contained in erythrocytes and binding oxygen. Like hematocrit, it plays a major role in the diagnosis of anemia. Its increase may indicate an oxygen deficiency.

  • Red blood cells (RBC) – red blood cells are responsible for the transport of oxygen and other substances and are the most numerous group of blood cells. Their number closely correlates with the hemoglobin index and has the same clinical significance.

  • Leukocytes (WBC) – white blood cells are responsible for immunity, fighting infections. This group includes several types of cells with different functions. The ratio of different forms of leukocytes to each other is called leukogram and is of high clinical importance in dogs.

    • Neutrophils – are very mobile, able to pass through tissue barriers, leave the bloodstream and have the ability to phagocytosis (absorption) of foreign agents such as viruses, bacteria, protozoa. There are 2 groups of neutrophils. Stab – immature neutrophils, they have just entered the bloodstream. If their number is increased, then the body reacts sharply to the disease, while the predominance of segmented (mature) forms of neutrophils will indicate a chronic course of the disease.

    • Eosinophils – a small group of large cells, the main purpose of which is the fight against multicellular parasites. Their increase almost always indicates a parasitic invasion. However, their normal level does not mean that the pet does not have parasites.

    • Basophils – cells responsible for the allergic reaction and its maintenance. In dogs, basophils increase very rarely, unlike people, even if there is an allergy.

    • Monocytes – large cells that are able to leave the bloodstream and penetrate into any focus of inflammation. They are the main component of pus. Increased with sepsis (bacteria entering the bloodstream).

    • Lymphocytes – Responsible for specific immunity. Having met with an infection, they “remember” the pathogen and learn to fight it. Their increase will indicate an infectious process, they can also increase with oncology. A decrease will speak about immunosuppression, bone marrow diseases, viruses.

  • Platelets – non-nuclear cells, the main function of which is to stop bleeding. They will always rise with blood loss, as a compensatory mechanism. They can be reduced for two reasons: either they are excessively lost (thrombotic poisons, blood loss, infections), or they are not formed enough (tumors, bone marrow diseases, etc.). But often they are underestimated erroneously if a blood clot has formed in the test tube (research artifact).

Tès san jeneral ak byochimik nan chen: dechifre endikatè yo

Analiz byochimik

The biochemistry of a dog’s blood will help determine or suggest diseases of individual organs, but in order to correctly decipher the results, you need to understand the essence of each indicator.

Faktè prensipal:

  • Albumen is a simple, water-soluble protein. It is involved in a huge number of processes, from cell nutrition to vitamin transport. Its increase has no clinical significance, while a decrease may indicate serious diseases with protein loss or a violation of its metabolism.

  • ALT (alanine aminotransferase) An enzyme found in most cells of the body. Its greatest amount is found in the cells of the liver, kidneys, cardiac and muscle muscles. The indicator increases with diseases of these organs (especially the liver). It also occurs after injury (due to muscle damage) and during hemolysis (destruction of red blood cells).

  • AST (aspartate aminotransferase) – an enzyme, like ALT, contained in the liver, muscles, myocardium, kidneys, red blood cells, and the intestinal wall. Its level almost always correlates with the level of ALT, but in myocarditis, the level of AST will be higher than the level of ALT, since AST is contained in a larger amount in the myocardium.

  • Alpha amylase – an enzyme produced in the pancreas (PZh), for the breakdown of carbohydrates. Amylase, as an indicator, has little clinical significance. It enters the bloodstream from the duodenum, respectively, its increase may be associated with an increase in intestinal permeability rather than with diseases of the pancreas.

  • Bilirubin is a pigment found in bile. Increases in diseases of the hepatobiliary system. With its increase, the mucous membranes take on a characteristic icteric (icteric) shade.

  • GGT (gamma-glutamyl transferase) – an enzyme found in the cells of the liver, pancreas, mammary gland, spleen, intestines, but not found in the myocardium and muscles. An increase in its level will indicate damage to the tissues in which it is contained.

  • Glucose – simple sugar, used as a source of energy. Changes in its amount in the blood will primarily indicate the state of metabolism. Deficiency will most often be associated with its insufficient intake (during hunger) or loss (poisoning, drugs). An increase will indicate serious diseases such as diabetes, kidney failure, etc.

  • Creatinine is a protein breakdown product. It is excreted by the kidneys, so if their work is disturbed, it will increase. However, it can be increased with dehydration, injuries, non-observance of hunger before a blood test.

  • Urea is the end product of protein breakdown. Urea is formed in the liver and excreted by the kidneys. Increases with the defeat of these organs. Decreases in liver failure.

  • Alkaline phosphatase – an enzyme contained in the cells of the liver, kidneys, intestines, pancreas, placenta, bones. In diseases of the gallbladder, alkaline phosphatase almost always rises. But it can also be increased during pregnancy, enteropathy, diseases of the oral cavity, during the growth period.

Tès san jeneral ak byochimik nan chen: dechifre endikatè yo

Norms of blood parameters

In general analysis

Table for deciphering the norms of indicators of a general blood test in dogs

endèksAdult dog, normalPuppy, norm
Emoglobin (g/L)120-18090-120
Ematokrit (%)35-5529-48
Eritrosit (milyon / µl)5.5-8.53.6-7.4
Lekosit (mil/µl)5.5-165.5-16
Netrofil kout kouto (%)0-30-3
Segman netwofil (%)60-7060-70
Monosit (%)3-103-10
Lenfosit (%)12-3012-30
Plakèt (mil/µl)140-480140-480
Tès san jeneral ak byochimik nan chen: dechifre endikatè yo

Nan analiz byochimik

Norms of indicators of a biochemical blood test in dogs

endèksAdult dog, normalPuppy, norm
Albumin (g/L)25-4015-40
LÒ (inite/l)10-6510-45
AST (inite/l)10-5010-23
Alfa-amilaz (inite/l)350-2000350-2000
Bilirubin dirèk

bilirubin total

(μmol/L)

GGT (inite/l)
Glikoz (mmol/l)4.3-6.62.8-12
ure (mmol/l)3-93-9
Kreatinin (μmol/L)33-13633-136
Fosfataz alkalin (u/l)10-8070-520
Kalsyòm (mmol/l)2.25-2.72.1-3.4
Fosfò (mmol/l)1.01-1.961.2-3.6

Deviations in blood counts

Analiz jeneral

Deciphering a blood test in dogs

endèksPi wo pase nòmal laAnba nòmal
Emoglobin

Ematokrit

Eritrosit

Si moun nan dezydrate

Ipoksi (maladi nan poumon, kè)

Timè BMC

Anemi nan maladi kwonik

Kwonik maladi ren

Pèt san

Emoliz

Iron Deficit

Maladi mwèl zo

Pwolonje jèn

leucocytesEnfeksyon (bakteri, viral)

repa resan

Gwosès

Pwosesis enflamatwa jeneral

Infections (eg, parvovirus enteritis)

Iminosupresyon

Maladi mwèl zo

senyen

Neutrophils yo kout koutoEnflamasyon egi

Enfeksyon egi

-
Neutrophils yo segmentéEnfamasyon kwonik

enfeksyon kwonik

Maladi KCM yo

Pèt san

Gen kèk enfeksyon

MonosietEnfeksyon

Timè

Blesi

Maladi KCM yo

pèt san

Iminosupresyon

LenfositEnfeksyon

Timè (ki gen ladan lenfom)

Maladi KCM yo

pèt san

Iminosupresyon

Enfeksyon viral

PlakètDènye pèt san/blesi

Maladi KCM yo

Si moun nan dezydrate

Pèt san

Sibstans emolitik (anpwazònman, kèk dwòg)

Maladi KCM yo

Vyolasyon pre-analytics

Tès san jeneral ak byochimik nan chen: dechifre endikatè yo

Analiz byochimik

Deciphering a biochemical blood test in dogs

endèksPi wo pase nòmal laAnba nòmal
albumènSi moun nan dezydrateFwa pèt

Enteropati oswa nefropati ki pèdi pwoteyin

Enfeksyon

blesi po anpil (pyoderma, atopy, ègzema)

Ensifizan konsomasyon nan pwoteyin

Efizyon/èdèm

Pèt san

ALTAtrofi fwa

Defisi piridoksin

Epatopati (neoplasi, epatit, lipidoz fwa, elatriye)

Ipoksi

Anpwazònman

pankreatit

Blese

AstAtrofi fwa

Defisi piridoksin

Epatopati

Anpwazonnman/entoksikasyon

Itilizasyon kortikoterapi

Ipoksi

Blesi

Emoliz

pankreatit

Alfa amilaz-Si moun nan dezydrate

pankreatit

Ren

Enteropati / rupture entesten

Epatopati

Pran kortikoterapi

Bilirubin-Emoliz

Maladi nan fwa a ak vezikulèr

ekstansyon GGT-Maladi nan fwa a ak vezikulèr
GlikozGrangou

Timè

sepsis

Fwa pèt

Gwosès an reta

Dyabèt

Anksyete/laperèz

Sendwòm epatokutane

Ipètiwoyidis

Rezistans ensilin (ak akromegali, hyperadrenocorticism, elatriye)

UreFwa pèt

Pèt pwoteyin

Asit

Grangou

Dezidratasyon/ipovolemi/chòk

Burns

Ensifizans ren ak lòt domaj nan ren

Anpwazònman

KreatininGwosès

Ipètiwoyidis

Kachoksi

Dezidratasyon/ipovolemi

Ren

Kè echèk

Gwo konsomasyon pwoteyin (manje vyann)

Fosfataz alkalin-Maladi nan fwa a ak vezikulèr

Terapi ak anticonvulsant

pankreatit

Jenn laj

Maladi dantè

Maladi zo (resorption, ka zo kase)

Timè

Tès san jeneral ak byochimik nan chen: dechifre endikatè yo

How to prepare a dog for the procedure?

The main rule before a blood test is to endure hunger.

For adult dogs weighing more than 10 kg, fasting should be 8-10 hours.

It is enough for small dogs to withstand hunger for 6-8 hours, they cannot starve for a long time.

For babies up to 4 months old, it is enough to maintain a hungry diet for 4-6 hours.

Water before analysis should not be limited.

Tès san jeneral ak byochimik nan chen: dechifre endikatè yo

Ki jan yo tire san?

Depending on the situation, the doctor may take an analysis from the vein of the front or rear limb.

First, a tourniquet is applied. The injection site of the needle is treated with alcohol, after which the blood is collected in test tubes.

Tès san jeneral ak byochimik nan chen: dechifre endikatè yo

The procedure, although unpleasant, is not very painful. Animals are more likely to be afraid of a tourniquet than a puncture with a needle. The task of the owners in this situation is to calm the pet as much as possible, talk to him and not be afraid yourself, if the dog feels that you are afraid, he will be even more scared.

Анализ крови собак. Берем кровь на биохимию. Советы ветеринара.

Repons kesyon yo poze souvan

Oktòb 6 2021

Mizajou: Oktòb NENPT, NAN

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